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MessagePublié: 11 Juin 2019, 23:21
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Bacterial Fungal Microbials Composite Microbials Others (Algae, Virus, and Protozoa)

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Cereals and Grains Oilseeds and Pulses Fruits and Vegetables Others

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SAN FRANCISCO, March 19 (Xinhua) -- High stress levels can have a critical impact not only on the surface Cheap Custom NHL Jerseys , making our skin age, but also on a molecular level, when stressed cells cannot cope with the pressure and perish much faster than the ones who can.


In a new research released on Thursday, scientists at the University of California, Berkeley, analyzed blood stem cells and found out that the cell's ability to repair damage in the mitochondria, their power source, was critical to their survival. Researchers tried to "relax" these stressed-out cells by slowing down the activity of their mitochondria.


"We found that by slowing down the activity of mitochondria in the blood stem cells of mice, we were able to enhance their capacity to handle stress and rejuvenate old blood. This confirms the significance of this pathway in the aging process Cheap Athentic NHL Jerseys ," said Danica Chen, an assistant professor with the Department of Nutritional Sciences and Toxicology.


This pathway lies mainly in the multitude of proteins that need to be folded properly for the mitochondria to function correctly. When the folding goes awry, the mitochondrial unfolded-protein response, or UPRmt, kicks in to boost the production of specific proteins to fix or remove the misfolded protein.


Researchers found that certain protein known as SIRT7 helps cells cope with the stress of unfolding the proteins in the mitochondria, helping those with higher levels of SIRT7 survive longer by making them "unwind." But the levels of SIRT7 decrease as people age.


"The protein level decreases as years go by," Chen said. "But if we increase this protein in blood stem cells we can make them live longer. Cells in general don't just die suddenly; they are submitted to high stress levels and lose their functions with age."


Chen does not want to encourage the thought that she and other researchers have found the "fountain of youth," but more of a new path for study.


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The study, published Thursday in the Science journal, is expected to help researchers gain more insight into the aging process, and even slow it down.


"Maybe in the future, once we are done with the clinical trial on humans and we can prove this research on other body stem cells, we will be able to produce a drug that can slow down this process by addressing this specific pathway," she said Cheap NHL Jerseys From China , adding that most likely that will not be in the near future.


Until this study, it was unclear which stress signals regulate the transition of stem cells to and from the quiescent mode, and how that relates to tissue regeneration in the aging process.


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4T Plus capsule is a substitute for the harmful

MessagePublié: 12 Août 2019, 01:09
par Kamignini
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